Test Code C3AHG Anti-C3 Coombs, Blood
Shipping Instructions
Specimen must arrive within 48 hours of collection.
Specimen Required
Only orderable as a reflex. For more information see DAT / Direct Coombs, Blood.
Container/Tube: Pink top (EDTA)
Specimen Volume: Entire specimen
Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.
Useful For
Detection of alloantibodies- or autoantibodies directed against red blood cell antigens
Evaluation of transfusion reactions
Evaluation of hemolytic anemia
Testing Algorithm
A positive direct Coombs result is further investigated using monospecific reagents with anti-IgG and anti-C3b-C3d specificity. The following tests may also be performed as part of a positive result: monospecific direct Coombs, antibody elution, antibody identification, and antibody absorption.
Method Name
Only orderable as a reflex. For more information see DAT / Direct Coombs, Blood.
Hemagglutination
Reporting Name
Anti-C3 CoombsSpecimen Minimum Volume
3 mL
Reject Due To
Gross hemolysis | Reject |
Reference Values
Only orderable as a reflex. For more information see DAT / Direct Coombs, Blood.
Negative
If positive due to C3, antibody identification may be performed
Performing Laboratory
MCHS- MankatoTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86880-Anti-C3 Coombs
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
C3AHG | Anti-C3 Coombs | 54410-6 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
C3AHG | Anti-C3 Coombs | 54410-6 |
Day(s) Performed
Varies