Test Code COKEP Cocaine and Metabolites, Plasma
Ordering Guidance
Additional drug panels and specific requests are available; call 800-533-1710.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Gray top (sodium fluoride/potassium oxalate plasma) (PST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL Plasma
Collection Instructions:
1. Within 2 hours of collection, centrifuge at 4° C and aliquot plasma into a plastic vial.
2. Freeze the specimen.
Secondary ID
624104Useful For
Confirming drug exposure involving stimulants such as cocaine, benzoylecgonine, m-hydroxy-benzoylecgonine, and cocaethylene
Special Instructions
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Cocaine and Metabolites, PSpecimen Type
PlasmaSpecimen Minimum Volume
Plasma: 0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Plasma | Frozen (preferred) | 28 days |
| Refrigerated | 6 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Negative
Positive results are reported with a quantitative result.
Cutoff concentrations:
Cocaine: 1.0 ng/mL
Benzoylecgonine: 1.0 ng/mL
Cocaethylene: 1.0 ng/mL
m-Hydroxybenzoylecgonine: 1.0 ng/mL
Day(s) Performed
Thursday
Report Available
3 to 9 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
G0480
80353 (if appropriate for select payers)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| COKEP | Cocaine and Metabolites, P | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 624105 | Cocaine | 3396-9 |
| 624106 | Benzoylecgonine | 3392-8 |
| 624107 | Cocaethylene | 27226-0 |
| 624108 | m-Hydroxybenzoylecgonine | 50593-3 |