Test Code IGGC IgG Coombs, Blood
Shipping Instructions
Specimen must arrive within 48 hours of draw.
Specimen Required
Only orderable as a reflex. For more information see DAT / Direct Coombs, Blood.
Container/Tube: Pink top (EDTA)
Specimen Volume: Entire specimen
Collection Instructions: Send whole blood specimen in original tube. Do not aliquot.
Useful For
Detection of alloantibodies or autoantibodies directed against red blood cell antigens
Evaluation of transfusion reactions
Evaluation of hemolytic anemia
Testing Algorithm
The monospecific IgG Coombs test is a reflex test for a positive direct Coombs test.
If the direct Coombs is positive due to IgG, then antibody elution will be performed.
The following tests may also be ordered and performed as part of a positive IgG Coombs: antibody elution, antibody identification, and antibody adsorption.
Method Name
Only orderable as a reflex. For more information see DAT / Direct Coombs, Blood.
IgG Coombs
Reporting Name
IgG CoombsSpecimen Type
Whole Blood EDTASpecimen Minimum Volume
3 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole Blood EDTA |
Reject Due To
Gross hemolysis | Reject |
Reference Values
Only orderable as a reflex. For more information see DAT / Direct Coombs, Blood.
Negative
If positive due to IgG, antibody identification and elution may be performed.
Performing Laboratory
MCHS- MankatoTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86880-Direct Coombs
86860-Antibody elution (if appropriate)
86870-Antibody identification (if appropriate)
86978-Adsorption (if appropriate)
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
IGGC | IgG Coombs | 55776-9 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
IGGC | IgG Coombs | 55776-9 |
Day(s) Performed
Monday through Sunday