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Test Code PNEUP Pneumonia Panel, PCR, Varies


Ordering Guidance


This test is appropriate for lower respiratory specimens only. For nasopharyngeal swab specimens, order RP / Respiratory Panel, PCR, Nasopharyngeal.

 

This assay is not predicted to detect severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), or SARS-CoV2, the virus that causes COVID-19. This test should only be ordered in cases of suspected acute lower respiratory tract infection and in conjunction with routine diagnostic testing, including respiratory culture and blood cultures.

 

It is not recommended that the following tests be concomitantly ordered when this test is ordered:

-HPFLU / Influenza Virus Type A and Type B, and Respiratory Syncytial Virus (RSV) RNA, Molecular Detection, PCR, Varies

-LADV / Adenovirus, Molecular Detection, PCR, Varies

-MPRP / Mycoplasma (Mycoplasmoides) pneumoniae with Macrolide Resistance Reflex, Molecular Detection, PCR, Varies



Additional Testing Requirements


It is recommended that the following testing be ordered with this test:

-SPUTS / Bacterial Culture, Aerobic, Respiratory with Antimicrobial Susceptibilities, Varies

-GRAM / Gram Stain, Varies



Shipping Instructions


Specimens must arrive within 24 hours of collection.



Necessary Information


Specimen source is required.



Specimen Required


Patient Preparation: Have patient rinse their mouth with water immediately prior to specimen collection. This reduces the number of contaminating oropharyngeal bacteria.

Specimen Type: Lower respiratory

Sources: Sputum, induced sputum, bronchoalveolar lavage, tracheal secretions

Container/Tube: Sterile container

Specimen Volume: Entire specimen

Collection Instructions: An early-morning expectorated sputum is preferred.


Useful For

Rapid detection of lower respiratory infections caused by the following:

-Acinetobacter calcoaceticus-baumannii

-Enterobacter cloacae complex

-Escherichia coli

-Haemophilus influenzae

-Klebsiella aerogenes

-Klebsiella oxytoca

-Klebsiella pneumoniae complex

-Moraxella catarrhalis

-Proteus species

-Pseudomonas aeruginosa

-Serratia marcescens

-Staphylococcus aureus

-Streptococcus agalactiae

-Streptococcus pneumoniae

-Streptococcus pyogenes

-Chlamydia pneumoniae

-Legionella pneumophila

-Mycoplasma pneumoniae

-CTX-M

-IMP

-KPC

-mecA/C and mec (SCCmec)-orfX right-extremity junction (MREJ)

-NDM

-OXA-48-like

-VIM

-Adenovirus

-Coronavirus HKU1

-Coronavirus NL63

-Coronavirus 229E

-Coronavirus OC43

-Human Metapneumovirus

-Human Rhinovirus/Enterovirus

-Influenza A (H1, H1-2009, H3)

-Influenza B

-Parainfluenza virus (serotypes 1, 2, 3, 4)

-Respiratory syncytial virus (RSV)

 

This test is not recommended as a test of cure.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
RPMPM M. pneumoniae Macrolide Resist PCR Yes No

Testing Algorithm

If testing is positive for Mycoplasma pneumoniae, RPMPM / Mycoplasma (Mycoplasmoides) pneumoniae Macrolide (Azithromycin) Resistance Prediction, Molecular Detection, PCR, Varies will be performed at an additional charge.

Method Name

Multiplex Polymerase Chain Reaction (PCR)

Reporting Name

Pneumonia Panel, PCR

Specimen Type

Varies

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Refrigerated (preferred) 24 hours
  Ambient  4 hours

Reject Due To

Bronchial washings
Upper respiratory specimens (eg, nasal, throat, nasopharyngeal)
Reject

Reference Values

Undetected (for all targets)

Day(s) Performed

Monday through Sunday

Report Available

1 to 2 days

Performing Laboratory

MCHS- Mankato

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

87999

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PNEUP Pneumonia Panel, PCR 92958-8

 

Result ID Test Result Name Result LOINC Value
PNSRC Specimen Source 31208-2
608833 Acinetobacter calcoaceticus-baumannii complex 96317-3
608834 Enterobacter cloacae complex 96318-1
608835 Escherichia coli 96319-9
608836 Haemophilus influenzae 96321-5
608837 Klebsiella aerogenes 96323-1
608838 Klebsiella oxytoca 96322-3
608839 Klebsiella pneumoniae complex 96324-9
608840 Moraxella catarrhalis 96325-6
608841 Proteus species 96327-2
608842 Pseudomonas aeruginosa 96326-4
608843 Serratia marcescens 96329-8
608844 Staphylococcus aureus complex 96328-0
608845 Streptococcus agalactiae 96320-7
608846 Streptococcus pneumoniae 96330-6
608847 Streptococcus pyogenes 96331-4
608848 CTX-M Resistance Gene 88250-6
608849 IMP Resistance Gene 85498-4
608850 KPC Resistance Gene 49617-4
608851 mecA Resistance Gene 96309-0
608852 NDM Resistance Gene 73982-1
608853 OXA-48-like Resistance Gene 85827-4
608854 VIM Resistance Gene 85501-5
608855 Chlamydia pneumoniae 92986-9
608856 Legionella pneumophila 92969-5
608857 Mycoplasma pneumoniae 92964-6
608858 Adenovirus 92987-7
608859 Coronavirus 92979-4
608860 Human Metapneumovirus 92978-6
608861 Human Rhinovirus/Enterovirus 92956-2
608862 Influenza A 92977-8
608863 Influenza B 92976-0
608864 Parainfluenza 92963-8
608865 Respiratory Syncytial Virus 92957-0
609747 Interpretation 59464-8