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Test Code RP Respiratory Panel, PCR, Nasopharyngeal


Ordering Guidance


This assay is not predicted to detect severe acute respiratory syndrome (SARS)-associated coronavirus or Middle East respiratory syndrome (MERS)-coronavirus.

 

This test is not intended for otherwise healthy, immunocompetent patients who are likely to have a mild, self-limited respiratory infection. If testing is desired, these patients should be tested using the more targeted diagnostic assays based on their exposure history and clinical presentation.

-FLUNP / Influenza Virus Type A and Type B, and Respiratory Syncytial Virus (RSV), Molecular Detection, PCR, Nasopharyngeal Swab

-BPRPV / Bordetella pertussis and Bordetella parapertussis, Molecular Detection, PCR, Varies

-MPRP / Mycoplasma (Mycoplasmoides) pneumoniae with Macrolide Resistance Reflex, Molecular Detection, PCR, Varies

-COVID / Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) RNA Detection, PCR, Varies

 

It is not recommended that the following tests be concomitantly ordered when this test is ordered:

-FLUNP / Influenza Virus Type A and Type B, and Respiratory Syncytial Virus (RSV), Molecular Detection, PCR, Nasopharyngeal Swab

-LADV / Adenovirus, Molecular Detection, PCR, Varies

-LENT / Enterovirus, Molecular Detection, PCR, Varies

-BPRPV / Bordetella pertussis and Bordetella parapertussis, Molecular Detection, PCR, Varies

-MPRP / Mycoplasma (Mycoplasmoides) pneumoniae with Macrolide Resistance Reflex, Molecular Detection, PCR, Varies

-COVID / Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) RNA Detection, PCR, Varies

 

This test is appropriate for nasopharyngeal swabs only. For bronchoalveolar lavage or bronchial washings specimens, order RPB / Respiratory Panel, PCR, Varies.



Shipping Instructions


Specimens that cannot be shipped refrigerated to Mayo Clinic Laboratories within 3 days (72 hours) should be frozen prior to shipment. Specimens received older than 72 hours (refrigerated) or older than 30 days (frozen) will be canceled.



Specimen Required


Specimen Type: Nasopharyngeal swab

Supplies:

-Culture Swab - Liquid Stuarts/Single Swab (NP Swab) (T515)

-M4-RT (T605)

-Nasopharyngeal Swab (Nylon Mini-Tip Swab) (T861)

Collection Container/Tube: Swab. See Additional Information for acceptable swab.

Submission Container/Tube: Transport medium. See Additional Information for acceptable media.

Specimen Volume: Nasopharyngeal swab in minimum volume of 1 mL of transport media

Collection Instructions:

1. Nasopharyngeal swab specimens should be collected according to standard technique and immediately placed into transport media and submitted for testing.

2. Submit swab in original container.

Additional Information:

If any nasopharyngeal swab or transport media not listed below is utilized, testing may be canceled.

-Acceptable nasopharyngeal (NP) swabs are Copan Rayon Swabs, Copan Nylon Flocked Swabs, Copan Polyester Swabs, Puritan Calcium Alginate Swabs, SteriFlock NP Swab

-Acceptable transport media are Remel M4, Remel M4-RT, Remel M5, Remel M6, BD Universal Viral Transport Media (VTM), Copan Universal Transport Media (UTM), PrimeStore Molecular Transport Medium (MTM)

-Acceptable collection and transport systems are Sigma-Virocult Viral Collection and Transport System (Swab and transport medium), Copan ESwab Sample Collection and Delivery System (Swab and Liquid Amies Medium), and BD ESwab Collection Kit (Flocked swab and Liquid Amies Medium).


Useful For

Rapid detection of respiratory infections caused by the following:

-Adenovirus

-Coronavirus (serotypes HKU1, NL63, 229E, OC43)

- SARS-CoV-2, the causative agent of COVID-19

-Human metapneumovirus

-Human rhinovirus/enterovirus

-Influenza A (H1, H1-2009, H3)

-Influenza B

-Parainfluenza virus (serotypes 1-4)

-Respiratory syncytial virus (RSV)

-Bordetella pertussis

-Bordetella parapertussis

-Chlamydia pneumoniae

-Mycoplasma pneumoniae

 

This test is not recommended as a test of cure.

Method Name

Multiplex Polymerase Chain Reaction (PCR)

Reporting Name

Respiratory Panel, PCR, NP

Reject Due To

Swabs other than NP swab (eg, any thick shafted swab such as an oropharyngeal swab or nasal swab)
Any transport media or NP swab type not listed in Specimen Required
Reject

Reference Values

Undetected (for all targets)

Performing Laboratory

MCHS- Mankato

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

0202U

LOINC Code Information

Test ID Test Order Name Order LOINC Value
RP Respiratory Panel, PCR, NP 82159-5

 

Result ID Test Result Name Result LOINC Value
SS021 Specimen Source 31208-2
609644 Adenovirus 82160-3
609645 Coronavirus 229E 82163-7
609646 Coronavirus HKU1 82161-1
609647 Coronavirus NL63 82162-9
609648 Coronavirus OC43 82164-5
609649 SARS Coronavirus-2 94565-9
609651 Human Metapneumovirus 82165-2
609650 Human Rhinovirus/ Enterovirus 82175-1
609652 Influenza A 82166-0
609653 Influenza B 82170-2
609654 Parainfluenza Virus 1 82171-0
609655 Parainfluenza Virus 2 82172-8
609656 Parainfluenza Virus 3 82173-6
609657 Parainfluenza Virus 4 82174-4
609658 Respiratory Syncytial Virus 82176-9
609659 Bordetella parapertussis 87621-9
609660 Bordetella pertussis 82179-3
609661 Chlamydia pneumoniae 82178-5
609662 Mycoplasma pneumoniae 82177-7
609663 Interpretation 59464-8

Specimen Type

Varies

Specimen Minimum Volume

See Specimen Required

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Refrigerated (preferred) 72 hours
  Frozen  30 days
  Ambient  4 hours

Testing Algorithm

If positive for Mycoplasma pneumoniae, M pneumoniae macrolide resistance will be performed at an additional charge.

 

For more information see Coronavirus Disease 2019 (COVID-19), Influenza, and Respiratory Syncytial Virus Testing Algorithm.

Day(s) Performed

Monday through Sunday

Report Available

1 to 2 days

Forms

If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
RPMPM M. pneumoniae Macrolide Resist PCR Yes No