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Test Code THCSD Thyroid Function Cascade, Initial Screen (with Thyroid Peroxidase Antibody), Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1.5 mL Serum

Collection Instructions:

1. Within 2 hours of collection, centrifuge the specimen.

2. For serum gel tubes, serum may sit on gel refrigerated or be aliquoted into a plastic vial.

3. For red top tubes, aliquot serum immediately into a plastic vial.


Useful For

Screening for a diagnosis of thyroid disease

Profile Information

Test ID Reporting Name Available Separately Always Performed
STSHC TSH, Sensitive, S Yes Yes

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
FRT4C T4 (Thyroxine), Free, S Yes No
TPOA Thyroperoxidase Ab, S Yes No
T3C T3 (Triiodothyronine), Total, S Yes No

Testing Algorithm

If thyrotropin (TSH, formerly thyroid-stimulating hormone) is less than 0.3 mIU/L, then free T4 (thyroxine) will be performed at an additional charge.

 

If FT4 is normal and the TSH is less than 0.1 mIU/L, then T3 (triiodothyronine) will be performed at an additional charge.

 

If TSH is greater than 4.2 mIU/L, then free T4 and thyroperoxidase antibodies will be performed at an additional charge.

Method Name

Electrochemiluminescent Immunoassay (ECLIA)

Reporting Name

Thyroid Function Cascade, S

Specimen Type

Serum

Specimen Minimum Volume

Serum: 1 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  30 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

0-5 days: 0.7-15.2 mIU/L

6 days-2 months: 0.7-11.0 mIU/L

3-11 months: 0.7-8.4 mIU/L

1-5 years: 0.7-6.0 mIU/L

6-10 years: 0.6-4.8 mIU/L

11-19 years: 0.5-4.3 mIU/L

≥20 years: 0.3-4.2 mIU/L

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Performing Laboratory

MCHS- Mankato

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

84443

84439-(if appropriate)

84480-(if appropriate)

86376 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
THCSD Thyroid Function Cascade, S 11579-0

 

Result ID Test Result Name Result LOINC Value
STSHC TSH, Sensitive, S 11579-0